What is Cagrilintide?
Research Focus: Weight Loss
Cagrilintide is a long-acting amylin analog currently under investigation for its potential role in chronic weight management and metabolic health. It mimics the action of the naturally occurring hormone amylin, which is co-secreted with insulin from pancreatic beta cells.
At a Glance
Cagrilintide is a synthetic peptide designed to have a prolonged half-life compared to native amylin. Amylin plays a crucial role in glucose homeostasis and satiety regulation by slowing gastric emptying and promoting feelings of fullness. This section provides a general overview of its research context.
About Cagrilintide
Cagrilintide is a synthetic peptide designed to have a prolonged half-life compared to native amylin. Amylin plays a crucial role in glucose homeostasis and satiety regulation by slowing gastric emptying and promoting feelings of fullness.
How It Works
Satiety Enhancement
Acts on receptors in the brainstem to increase feelings of satiety, leading to reduced food intake.
Gastric Emptying Modulation
Slows the rate at which food leaves the stomach, contributing to prolonged fullness and reduced post-meal glucose spikes.
Current Research Insights
Combination Therapy Potential
Early research suggests Cagrilintide, particularly when combined with other GLP-1 agonists (like Semaglutide in CagriSema), shows promising results in achieving significant weight reduction compared to monotherapy.
Areas of Study
Chronic Weight Management
Investigated as a standalone or combination therapy for obesity.
Metabolic Improvement
Studied for improving metabolic markers in individuals with type 2 diabetes.
Cagrilintide is strictly intended for laboratory and clinical research:
- Available exclusively from authorized research suppliers
- Not FDA-approved for general therapeutic use
- Comprehensive safety, efficacy, and dosage guidelines remain under ongoing investigation
FAQs
Research
- Clinical trials investigating Cagrilintide monotherapy and combination therapy (CagriSema) for weight management.
- Studies on the role of amylin analogs in appetite regulation and glucose homeostasis.
(The above references are representative and support the research context of this peptide, GLP hormone or regenerative therapy. All claims are for research purposes only and do not imply approved medical use.)