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What is IGF-1 LR3?

Research Focus: Muscle, Tissue Repair

Benefits, Research & Legality (2025 Guide)

Insulin-like Growth Factor 1 Long R3 (IGF-1 LR3) is a modified, long-acting analog of IGF-1. It is highly studied for its potent anabolic effects on muscle and tissue repair.

At a Glance

IGF-1 is a hormone similar in structure to insulin, primarily produced by the liver in response to GH. The LR3 modification prevents it from binding strongly to IGF-binding proteins, significantly extending its half-life and bioavailability. This section provides a general overview of its research context.

About IGF-1 LR3

IGF-1 is a hormone similar in structure to insulin, primarily produced by the liver in response to GH. The LR3 modification prevents it from binding strongly to IGF-binding proteins, significantly extending its half-life and bioavailability.

How It Works

Anabolic Signaling

Activates the IGF-1 receptor, promoting protein synthesis, cell proliferation, and muscle cell differentiation.

Extended Half-Life

The R3 modification allows it to circulate longer in the bloodstream, providing sustained anabolic signaling.

Current Research Insights

Localized and Systemic Anabolism

Researchers use IGF-1 LR3 to study both systemic muscle growth and localized tissue repair when injected near an injury site.

Areas of Study

Muscle Hypertrophy

Investigated for maximizing muscle growth and recovery.

Tissue Regeneration

Studied for accelerating the repair of damaged tendons, ligaments, and cartilage.

Research Use Only Section

IGF-1 LR3 is strictly intended for laboratory and clinical research:

  • Available exclusively from authorized research suppliers
  • Not FDA-approved for general therapeutic use
  • Comprehensive safety, efficacy, and dosage guidelines remain under ongoing investigation

FAQs

Research

  • Studies on IGF-1 analogs and their role in muscle protein synthesis.
  • Research into the pharmacokinetics of IGF-1 LR3 and its binding protein affinity.

(The above references are representative and support the research context of this peptide, GLP hormone or regenerative therapy. All claims are for research purposes only and do not imply approved medical use.)