What is LL-37?
Research Focus: Immune, Tissue Repair, Wounds
LL-37 is the only cathelicidin peptide found in humans. It is a broad-spectrum antimicrobial peptide and a key component of the innate immune system, studied for its powerful immune-modulating and wound-healing effects.
At a Glance
LL-37 is released by immune cells and epithelial cells in response to infection or injury. It directly kills pathogens and also acts as a signaling molecule to recruit immune cells and promote tissue repair. This section provides a general overview of its research context.
About LL-37
LL-37 is released by immune cells and epithelial cells in response to infection or injury. It directly kills pathogens and also acts as a signaling molecule to recruit immune cells and promote tissue repair.
How It Works
Direct Antimicrobial Action
Disrupts the membranes of bacteria, viruses, and fungi.
Immune Modulation
Regulates the inflammatory response, promoting healing while fighting infection.
Angiogenesis and Epithelialization
Promotes the formation of new blood vessels and the growth of new skin cells, accelerating wound closure.
Current Research Insights
Innate Immunity Booster
LL-37 is a major focus in research for developing new strategies against antibiotic-resistant bacteria and chronic wounds.
Areas of Study
Chronic Wounds and Burns
Investigated for accelerating healing and preventing infection.
Autoimmune and Inflammatory Diseases
Studied for its ability to modulate the immune system.
Infections
Researching its broad-spectrum activity against various pathogens.
LL-37 is strictly intended for laboratory and clinical research:
- Available exclusively from authorized research suppliers
- Not FDA-approved for general therapeutic use
- Comprehensive safety, efficacy, and dosage guidelines remain under ongoing investigation
FAQs
Research
- Studies on LL-37's role in innate immunity and antimicrobial defense.
- Research into the wound healing and angiogenic properties of cathelicidins.
(The above references are representative and support the research context of this peptide, GLP hormone or regenerative therapy. All claims are for research purposes only and do not imply approved medical use.)