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What is Melanotan-II?

Research Focus: Skin Pigmentation, Sexual Health

Benefits, Research & Legality (2025 Guide)

Melanotan-II (MT-II) is a synthetic analog of the alpha-melanocyte-stimulating hormone (α-MSH). It is studied for its ability to induce skin tanning and its effects on sexual function.

At a Glance

MT-II acts as a non-selective agonist of melanocortin receptors (MC1, MC3, MC4, MC5). Activation of MC1 leads to increased melanin production (tanning), while activation of MC3/MC4 is linked to sexual arousal and appetite suppression. This section provides a general overview of its research context.

About Melanotan-II

MT-II acts as a non-selective agonist of melanocortin receptors (MC1, MC3, MC4, MC5). Activation of MC1 leads to increased melanin production (tanning), while activation of MC3/MC4 is linked to sexual arousal and appetite suppression.

How It Works

Melanogenesis

Stimulates melanocytes to produce melanin, leading to darker skin pigmentation.

Sexual Arousal

Activation of central melanocortin receptors (MC3/MC4) is linked to pro-erectile and pro-sexual effects.

Current Research Insights

Dual Action Peptide

MT-II is unique in research for its dual effects on pigmentation and sexual function, making it a popular subject in both aesthetic and sexual health studies.

Areas of Study

Skin Protection

Investigated for increasing melanin to potentially reduce UV damage.

Sexual Dysfunction

Studied for treating erectile dysfunction and female hypoactive sexual desire disorder.

Research Use Only Section

Melanotan-II is strictly intended for laboratory and clinical research:

  • Available exclusively from authorized research suppliers
  • Not FDA-approved for general therapeutic use
  • Comprehensive safety, efficacy, and dosage guidelines remain under ongoing investigation

FAQs

Research

  • Studies on melanocortin receptor agonists and their effects on pigmentation and sexual function.
  • Research into the central effects of MT-II on appetite and satiety.

(The above references are representative and support the research context of this peptide, GLP hormone or regenerative therapy. All claims are for research purposes only and do not imply approved medical use.)