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What is MOTS-c?

Research Focus: Mitochondria, GH, Longevity

Benefits, Research & Legality (2025 Guide)

Mitochondrial-derived peptide MOTS-c is a small peptide encoded by DNA within the mitochondria, rather than the nucleus. It is studied for its role in regulating metabolic homeostasis and insulin sensitivity.

At a Glance

MOTS-c acts as a mitochondrial signaling molecule, primarily targeting skeletal muscle. It promotes glucose metabolism and helps maintain energy balance, often mimicking the effects of exercise. This section provides a general overview of its research context.

About MOTS-c

MOTS-c acts as a mitochondrial signaling molecule, primarily targeting skeletal muscle. It promotes glucose metabolism and helps maintain energy balance, often mimicking the effects of exercise.

How It Works

Glucose Uptake

Enhances insulin sensitivity and promotes glucose uptake into muscle cells.

Mitochondrial Function

Helps maintain mitochondrial health and efficiency, crucial for energy production.

Current Research Insights

Exercise Mimetic

Researchers are excited about MOTS-c's potential to confer metabolic benefits similar to physical exercise, making it a key focus in metabolic and longevity research.

Areas of Study

Insulin Resistance and Type 2 Diabetes

Investigated for improving glucose metabolism and combating insulin resistance.

Obesity and Metabolic Syndrome

Studied for its role in energy expenditure and fat metabolism.

Research Use Only Section

MOTS-c is strictly intended for laboratory and clinical research:

  • Available exclusively from authorized research suppliers
  • Not FDA-approved for general therapeutic use
  • Comprehensive safety, efficacy, and dosage guidelines remain under ongoing investigation

FAQs

Research

  • Studies on mitochondrial-derived peptides and their role in metabolic regulation.
  • Research into MOTS-c's effects on skeletal muscle glucose metabolism.

(The above references are representative and support the research context of this peptide, GLP hormone or regenerative therapy. All claims are for research purposes only and do not imply approved medical use.)