What is NAD+?
Research Focus: Cellular Health, Cognitive, Longevity
Nicotinamide Adenine Dinucleotide (NAD+) is a critical coenzyme found in every cell in the body, essential for energy production, DNA repair, and cellular signaling. Levels decline significantly with age.
At a Glance
NAD+ exists in two forms: NAD+ (oxidized) and NADH (reduced). It is vital for redox reactions, acting as a shuttle for electrons in the electron transport chain (ATP production) and serving as a substrate for longevity enzymes like sirtuins and PARPs. This section provides a general overview of its research context.
About NAD+
NAD+ exists in two forms: NAD+ (oxidized) and NADH (reduced). It is vital for redox reactions, acting as a shuttle for electrons in the electron transport chain (ATP production) and serving as a substrate for longevity enzymes like sirtuins and PARPs.
How It Works
Energy Metabolism
Essential for converting nutrients into cellular energy (ATP).
DNA Repair
Required by PARP enzymes to repair damaged DNA.
Sirtuin Activation
Activates sirtuins, a class of proteins linked to longevity, metabolic health, and gene expression regulation.
Current Research Insights
Cellular Fuel
NAD+ is considered a foundational molecule in anti-aging research, with supplementation being studied as a way to restore youthful cellular function.
Areas of Study
Anti-Aging and Longevity
Investigated for improving cellular resilience and healthspan.
Neuroprotection
Studied for improving cognitive function and protecting against neurodegeneration.
Fatigue and Energy
Researching its role in combating chronic fatigue and improving physical endurance.
NAD+ is strictly intended for laboratory and clinical research:
- Available exclusively from authorized research suppliers
- Not FDA-approved for general therapeutic use
- Comprehensive safety, efficacy, and dosage guidelines remain under ongoing investigation
FAQs
Research
- Studies on NAD+ metabolism and its role in aging and disease.
- Research into the effects of NAD+ precursors on sirtuin activity and DNA repair.
(The above references are representative and support the research context of this peptide, GLP hormone or regenerative therapy. All claims are for research purposes only and do not imply approved medical use.)