What is PT-141?
Research Focus: Sexual Health
PT-141 (Bremelanotide) is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH). It is studied specifically for treating sexual dysfunction in both men and women.
At a Glance
Unlike Melanotan-II, PT-141 is a selective agonist of the MC4 receptor (and MC3), which is primarily responsible for central nervous system effects related to sexual arousal, rather than pigmentation (MC1). This section provides a general overview of its research context.
About PT-141
Unlike Melanotan-II, PT-141 is a selective agonist of the MC4 receptor (and MC3), which is primarily responsible for central nervous system effects related to sexual arousal, rather than pigmentation (MC1).
How It Works
Central Arousal
Acts on melanocortin receptors in the brain to increase sexual desire and arousal.
Hormone Independent
Its mechanism of action is central and does not rely on modulating sex hormones (like testosterone or estrogen).
Current Research Insights
Non-Vascular Mechanism
Researchers value PT-141 because it addresses the psychological/central component of sexual dysfunction, unlike drugs that only target blood flow (e.g., Viagra).
Areas of Study
Female Hypoactive Sexual Desire Disorder (HSDD)
Investigated for increasing libido and arousal in women.
Erectile Dysfunction (ED)
Studied for treating ED, particularly in cases where vascular issues are not the primary cause.
PT-141 is strictly intended for laboratory and clinical research:
- Available exclusively from authorized research suppliers
- Not FDA-approved for general therapeutic use
- Comprehensive safety, efficacy, and dosage guidelines remain under ongoing investigation
FAQs
Research
- Clinical trials on Bremelanotide for sexual dysfunction.
- Studies on the role of central melanocortin receptors in sexual behavior.
(The above references are representative and support the research context of this peptide, GLP hormone or regenerative therapy. All claims are for research purposes only and do not imply approved medical use.)