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What is SS-31?

Research Focus: Mitochondria, Inflammation

Benefits, Research & Legality (2025 Guide)

SS-31 (also known as Elamipretide) is a small, cell-permeable peptide that selectively targets the inner mitochondrial membrane. It is studied for its ability to protect and restore mitochondrial function.

At a Glance

SS-31 binds to cardiolipin, a phospholipid essential for the structure and function of the inner mitochondrial membrane. By stabilizing cardiolipin, SS-31 helps maintain the integrity of the electron transport chain and reduces oxidative stress. This section provides a general overview of its research context.

About SS-31

SS-31 binds to cardiolipin, a phospholipid essential for the structure and function of the inner mitochondrial membrane. By stabilizing cardiolipin, SS-31 helps maintain the integrity of the electron transport chain and reduces oxidative stress.

How It Works

Mitochondrial Stabilization

Binds to cardiolipin, stabilizing the inner membrane and improving the efficiency of ATP production.

Reduced ROS Production

Decreases the production of reactive oxygen species (ROS) by the mitochondria, reducing cellular damage and inflammation.

Current Research Insights

Mitochondrial Rescue

SS-31 is a key focus in research targeting diseases driven by mitochondrial dysfunction, such as heart failure and neurodegeneration.

Areas of Study

Age-Related Diseases

Investigated for improving function in organs with high energy demands, like the heart and brain.

Chronic Inflammation

Studied for its ability to reduce oxidative stress, a major driver of inflammation.

Research Use Only Section

SS-31 is strictly intended for laboratory and clinical research:

  • Available exclusively from authorized research suppliers
  • Not FDA-approved for general therapeutic use
  • Comprehensive safety, efficacy, and dosage guidelines remain under ongoing investigation

FAQs

Research

  • Studies on SS-31 and its mechanism of action on cardiolipin and mitochondrial function.
  • Research into Elamipretide's therapeutic potential in cardiovascular and renal diseases.

(The above references are representative and support the research context of this peptide, GLP hormone or regenerative therapy. All claims are for research purposes only and do not imply approved medical use.)